Brief News

9/10/2020

Vasopressin can abruptly be discontinued in septic shock.

9/3/2020

FDA grants emergency authorization for blood plasma as COVID-19, though questions emerge.

8/20/2020

Tocilizumab in hospitalized adults with severe COVID-19–associated pneumonia did not meet its primary end point of improved clinical status or key secondary end points.

8/8/2020

Convalescent plasma fails to reduce Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19.

8/3/2020

Continuous Infusion of Methylene Blue may help in Refractory Septic Shock.

7/31/2020

Treating subclinical hypothyroidism in Acute MI doesnt help.

7/30/2020

No difference between hydrocortisone versus methylprednisolone on clinical outcomes in oncology patients with septic shock.

7/22/2020

Inhaled Interferon beta shows promise in COVID 19.

7/22/2020

Type 1 interferon dysregulation leads to severe COVID 19.

07/16/2020

37% COVID patients had PE on CTPA.

7/9/2020

Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection improves outcome.

 

6/28/2020

 

Colchicine in COVID 19 improved time to clinical deterioration.

6/24/2020

Tocilizumab improves survival in mechanically ventilated COVID 19 patients with cytokine storm.

6/20/2020

Covid-19: Low dose steroid dexamethasone cuts death in ventilated patients.

6/15/2020

Auxora( inhibitor of calcium release-activated calcium (CRAC) channels) and Acalabrutinib(Bruton tyrosine kinase “BTK” inhibitor) may work against COVID.

6/9/2020

Rifabutin may be useful against Acinetobacter baumannii.

6/1/2020

Artificial Intelligence as good as radiologists in detecting Lung Infection in Supine Chest Radiographs of Critically Ill Patients. 

5/22/2020

High-Dose Vitamin C Therapy in Adult Patients is not associated with any harm.

5/18/2020

Operative Surgery Is Rarely Required in the Acute Management of Diverticulitis.

5/1/2020

Remdesivir accelerates recovery in COVID 19.

4/11/2020

 

Cytokine absorbing filter in patients with pneumococcal sepsis undergoing ECMO may reduce mortality. 

3/25/2020

Nebulized Eucalyptus prevents Ventilator-associated Pneumonia.

3/6/2020

Significant higher risk for CLABSI associated with a second CVC.

 

3/4/2020

Aspirin as good as other anticoagulants for Venous Thromboembolism Prophylaxis After Total Hip and Knee Replacement.

3/3/2020

Interferon Beta Tx Shows No Benefit in ARDS.

2/20/2020

First spontaneous unilateral moderate to large pneumothorax can be treated conservatively.

2/14/2020

 

Preoperative C-reactive protein predicts early postoperative outcomes after pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension. 

2/1/2020

Chest compressions should start when systolic arterial blood pressure is below 50 mm Hg in the anaesthetised patient.

1/6/2020

High-Dose Vitamin C Therapy Was Associated with Reduced Mortality in Patients with Severe Burns.

12/31/2019

In adults with severe TBI, prehospital rapid sequence intubation by paramedics increases the rate of favorable neurologic outcome.

12/25/2019

Succinylcholine may be slightly better than Rocuronium for out of hospital intubation.

12/21/2019

 

Increasing D Dimer cut off to 1000 can safely eliminate more CTs.

12/20/2019

Tranexamic Acid Improves Outcomes in TBI.

12/19/2019

Prophylactic Acyclovir does not work for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation.

12/15/2019

No benefit of Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients.

12/9/2019

33 degree targeted temperature shows better neurological outcome in a retrospective study.

12/6/2019

Admission hypothermia associated with worse outcome than hyperthermia.

11/30/2019

Continuous IV administration of epinephrine as inotropic/vasopressor agent is not associated with a worse outcome in critically ill patients.

11/26/2019

Low-Dose Colchicine after Myocardial Infarction significantly lower risk of ischemic cardiovascular events.

11/25/2019

Beta blockers double the risk of Acute Exacerbations of COPD.

11/24/2019

FDA approves Cefiderocol for cUTI. New hope for MDR GNBs.

11/20/2019

 

Intravenous contrast does not lead to permanent dialysis dependency in patients with acute kidney injury.

11/19/2019

Tranexamic acid may improve mortality in patients with hemoptysis.

11/18/2019

Dexmedetomidine Reduces Atrial Fibrillation After Adult Cardiac Surgery. 

11/17/2019

Central location of ETT causes more mouth ulcers.

11/15/2019

ICU beds with copper surfaces may retain fewer bacteria. 

11/14/2019

Avoid probiotics in ICU to prevent central line infections.

11/7/2019

Vit E acetate identified as possible culprit for Vaping induced lung injury.

11/5/2019

AI outperforms clinicians’ judgment in triaging postoperative patients for intensive care.

11/3/2019

Lower Urinary chloride concentration as a prognostic marker(associated with increased mortality, cutoff 53mEQ/ L) in critically ill patients. 

Elevated plasma Histone H4 levels correlate with development of septic cardiomyopathy.

Bacteriophages Improve Outcomes in Experimental Staphylococcus aureus Ventilator-associated Pneumonia

1/21/2019

Safety of the Peripheral Administration of Vasopressor Agents.