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Landmark Articles

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In this space, we will post summaries of landmark articles from field of critical care.

Brief News

10/2/2024

Liberal blood transfusion may improve neurological outcome in acute brain injury patients.

9/25/2024

Early mechanical ventilation(Day 1) in sepsis may improve outcome.

9/10/2024

Risk of atrial fibrillation after CABG same for low(3.6) vs high(4.5) potassium level.

9/1/2024

Intubation during transport leads to hemodynamic collapse.

8/20/2024

Moderate IV Fluid Resuscitation (4 litres) Is Associated With Decreased Sepsis Mortality.

7/15/2024

Pantoprazole reduces GI bleeding in intubated patients without improving mortality.

6/15/2024

Intravenous Amino Acids prevent kidney injury in cardiac surgery patients.

6/11/2024

Noninvasive Ventilation before intubation prevents hypoxia in emergent intubation.

5/19/2024

Video laryngoscopy better, in operating room as well.

4/19/2024

Hydrocortisone plus fludrocortisone improve mortality in CAP with Septic Shock.

3/20/2024

No difference in mortality between high(PaO2 90) vs low(PaO2 60) in intubated Covid patients.

3/1/2024

Probabilities of survival rapidly declines over time during CPR, less than 1% at 39 minutes.

2/1/2024

Haloperidol improves mortality in patients with delirium admitted to ICU.

1/2/2024

Etomidate use for endotracheal intubation in critically ill patients increases mortality.

12/23/2023

Daily toothbrushing reduces pneumonia and improves mortality in ICU.

12/11/2023

Prophylactic Minocycline may reduce ICU delirium.

12/3/2023

Prone positioning during ECMO for ARDS does not help.

11/26/2023

Small-Volume Blood Collection Tubes Reduce Transfusions in Intensive Care.

11/19/2023

Resuscitative endovascular balloon occlusion of the aorta (REBOA) does not improve mortality in trauma patients with exsanguinating hemorrhage.

11/18/2023

Early and empirical high-dose cryoprecipitate in trauma does not improve survival.

11/01/2023

Inhaled Amikacin reduces the incidence of Ventilator-Associated Pneumonia.

10/24/2023

Convalescent Plasma reduces mortality by 10% in Covid-19 on Mechanically Ventilation.

10/21/2023

Hydrocortisone outperforms(mortality benefit) all other steroids for community acquired pneumonia.

10/15/2023

No difference between Cefepime and Pip-Tazo in terms of acute kidney injury, need for renal replacement therapy, or death in sepsis.

10/14/2023

Betablockers harmful in septic shock treated with norepinephrine.

10/1/2023

PEEP of 10 ideal for ARDS patients on VV ECMO.

9/19/2023

Propafanone as good as Amiodarone for AFib in septic shock.

9/1/2023

Obese patients who need ECMO have better outcome than patients with normal BMI.

8/20/2023

Surgical rib fixation does not improve QOL in severe chest injury.

7/2/2023

Procalcitonin at admission not reliable for capturing bacteremia in sepsis.

6/28/2023

Catheter-directed thrombolysis compared with systemic thrombolysis and anticoagulation improves survival in in patients with intermediate- or high-risk pulmonary embolism.

6/12/2023

Continuous infusion of meropenem does not improve outcome in sepsis.

6/5/2023

Prehospital administration of tranexamic acid in severe trauma does not improve outcome.

6/1/2023

No difference between anakinra plus standard care vs standard care alone for reducing mortality risk or need for mechanical ventilation among patients hospitalized with severe COVID-19 pneumonia and hyperinflammation.

5/20/2023

Mannitol and Hypertonic Saline equally effective in TBI.

5/17/2023

No difference between higher dose methylprednisone and standard dexamethasone in COVID 19.

5/15/2023

Secondary bacterial pneumonia, not cytokine storm caused deaths in COVID 19.

4/12/2023

BCG vaccination doesn’t prevent COVID.

3/31/2023

High dose DVT prophylaxis better than standard dose in COVID hypoxic respiratory failure.

3/20/2023

Fludrocortisone added to hydrocortisone was associated with increased hospital survival, shorter length of stay, and decreased shock duration in septic shock.

2/28/2023

Condom catheters can be deadly.

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